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KMID : 0381319830220030070
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Korean Journal of Occupational Health
1983 Volume.22 No. 3 p.70 ~ p.75
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Interrelationships between parameters indicative of lead absorption and intoxication in non-occupationaly lead exposed subjects.
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Abstract
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In order to evaluate the interrelationships between parameters indicative of lead absorption and intoxication in non-occupationally lead exposed subject, we examined lead in blood(PbB), lead in urine(PbU), δ-aminolevuilnic acid in urine(ALAU) and coproporphyrin in urine(CPU) of 109 subjects who were admitted to the hospitals or visited the outpatient clinics with the clinical impression of lead poisoning without any occupational history of lead exposure.
The results obtained were as follows:
1. If ALAU of 5 ㎎/ℓ and CPU of 150㎍/ℓ were selected as response level in the doseresponse effects of lead on hematopoietic system, about 50％ of subjects whose PbB were in the range of 30-40㎍/㎗ showed positive responses. On the other hand, if ALAU of 10㎎/ℓ and CPU of 300㎍/ℓ were selected as response level, 30％ of subjects whose PbB were in the range of 50-60㎍/㎗ showed positive responses.
2. If an ALAU of over 10㎎/ℓ and CPU of over 300㎍/ℓ are cosidered as an unacceptable limit, the present study suggested that a PbB of 50-60㎍/㎗ would be the practical limit for biological monitoring.
3. The interrelationship between PbU or ALAU or CPU was better explained either by a segmental straight function or second degree regression rather than simple straight regression.
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